Extract: The enological importance of the biogenic amines in wines is due to their possible toxicological risks and the possibility of the relationship between high amine content and unsanitary conditions during wine production procedures. The aim of this work is to determine the biogenic amines profile of quality red Turkish wines by using high-performance liquid chromatography with pre-column derivatization and photodiode array detection. The levels of biogenic amines in Turkish red wines were investigated for the first time.